Zosyn and vancomycin iv compatibility pdf

Piperacillintazobactam and vancomycin are reliably compatible. Ysite compatibility of vancomycin and piperacillin. Ysite injection drug compatibility chart for general wards. Published vancomycin and pt compatibility data, describing varying concentrations of each drug, demonstrate inconsistent results. Vancomycin and piperacillintazobactam combination therapy.

Keywords compatibility, piperacillintazobactam, vancomycin, ysite, zosyn. Physical compatibility of vancomycin and piperacillin sodium. Vancomycin and piperacillintazobactam are common empiric antibiotics in hospitalized pediatric patients. Xx pharmaceutical services extended infusion piperacillintazobactam protocol. Check tubing below ysite carefully for discoloration, cloudiness or precipitation. Zosyn intravenous interactions with other medication. Vancomycin hydrochloride and piperacillin sodiumtazobactam were reconstituted with 0. Ysite incompatibility was greater for the tested concentrations of piperacillin tazobactam and vancomycin when 5% dextrose was used as the diluent. Ysite injection drug compatibility chart for general. Ysite compatibility of vancomycin and piperacillintazobactam at. The usual duration of zosyn treatment is from 7 to 10 days.

Vancomycin and piperacillintazobactam were tested using simulated and actual ysite infusion methodologies. Each dose was reconstituted and diluted to a volume of 37. Highlights of prescribing information these highlights do. Compatibility depends upon many factors including temperature, ph, iv fluid, concentration, order of mixing and brand of. Compatibility depends upon many factors including temperature, ph, iv fluid, concentration, order of mixing and brand of drug. Simulated ysite compatibility of vancomycin and piperacillin.

Physical compatibility of vancomycin and piperacillin. Zosyn piperacillin and tazobactam for injection, for intravenous use. The usual total daily dose of zosyn for adults is 3. Pdf ysite incompatibility between premix concentrations of. Adult extended infusion piperacillintazobactam protocol policy xx.

Please confirm that you would like to log out of medscape. Original article simulated ysite compatibility of vancomycin and. Extendedinfusion piperacillintazobactam zosyn compatibility. Zosyn should be administered by intravenous infusion over 30 minutes. When dextrose 5% for injection was used as the diluent, vancomycin 4 mgml was ysite compatible with piperacillintazobactam 16, 30, and. Additionally, no information exists on the compatibility of piperacillintazobactam and micafungin. Stability and compatibility of vancomycin for administration by continuous infusion article in journal of antimicrobial chemotherapy 685 january 20 with. Iv ysite infusion solution compatibility data infusion solution compatible. Pdf download for simulated ysite compatibility of vancomycin and. Zosyn piperacillin and tazobactam for injection and zosyn piperacillin and tazobactam injection are injectable antibacterial combination products consisting of the semisynthetic antibacterial piperacillin sodium and the. Zosyn reconstituted from bulk and single vials can be used in ambulatory intravenous infusion pumps.